梁欢欢教授简介

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梁欢欢教授

2017年10月任药学院(深圳)“百人计划”教授、博导 。以(共同)第一或通讯作者在Angew Chem Int Ed Engl,Molecular Cell,Cell Research,Nature Communications,Genes & Development, Science Signaling 和JBC等期刊发表论文10篇。

电子邮箱

lianghh26@mail.sysu.edu.cn

学科专业

药物化学

研究方向

感染免疫和结构生物学

代表论著

  1. Xiahou Z, Wang X, Shen J, Zhu X, Xu F, Tian Y, Liu Y*, Liang H*. (2017) NMI and IFP35 serve as proinflammatory DAMPs during cellular infection and injury. Nature Communications. 16;8(1):950. doi: 10.1038/s41467-017-00930-9.

  2. Guan C, Li J, Sun D, Liu Y*, Liang H*. (2017) The structure and polymerase-recognition mechanism of the crucial adaptor protein AND-1 in the human replisome. J Biol Chem. 9;292(23):9627-9636. doi: 10.1074/jbc.M116.758524.

  3. Yang M, Feng F, Liu Y, Wang H, Yang Z, Hou W*, Liang H*.  (2016) pH-dependent conformational changes of a Thogoto virus matrix protein reveal mechanisms of viral assembly and uncoating. J Gen Virol. 97(9):2149-56. doi: 10.1099/jgv.0.000551.

  4. Chang S#, Sun D#, Liang H#, Wang J, Li J, Guo L, Wang X, Guan C, Boruah BM, Yuan L, Feng F, Yang M, Wang L, Wang Y, Wojdyla J, Li L, Wang J, Wang M, Cheng G, Wang HW, Liu Y. (2015) Cryo-EM structure of influenza virus RNA polymerase complex at 4.3 Å resolution. Mol Cell. 5;57(5):925-35. doi: 10.1016/j.molcel.2014.12.031.

  5. Feng F, Yuan L, Wang YE, Crowley C, Lv Z, Li J, Liu Y, Cheng G, Zeng S, Liang H*. (2013) Crystal structure and nucleotide selectivity of human IFIT5/ISG58. Cell Res. 23(8):1055-8. doi: 10.1038/cr.2013.80.