深圳市海外高层次人才,现任中山大学副教授,硕士生导师。博士毕业于伦敦大学学院(UCL)。曾任英国Intract Pharma制药公司首席研究员,慕恩(广州)生物科技有限公司技术顾问。荣获伦敦大学学院Overseas Research Scholarship、Originality of Presentation Award、国家留学生基金委建设高水平大学项目攻博奖学金等。研究方向主要为口服药物递送、局部长效药物制剂、胃肠道生理及脑-肠轴机制。近年来主持或参加国家自然科学基金青年基金、面上项目、军委科技委重点基础研究项目、深圳市科技计划基础研究重点项目、企业横向合作项目多项,以第一作者或通讯作者在Journal of Controlled Release, International Journal of Pharmaceutics, Molecular Pharmaceutics等期刊共发表学术论文20余篇。

 

电子邮箱

maiy6@mail.sysu.edu.cn

 

学科专业

药剂学,生物药剂学

 

个人经历

(1)2009.09-2013.06,南方医科大学,药学院,药物制剂专业,获学士学位

(2)2013.11-2017.02,伦敦大学学院,药剂学院,药剂学系,获博士学位

(3)2017.03-2018.10,Intract Pharma Ltd,首席研究员(Leading Scientist)

(4)2019.01-2023.08,中山大学,药学院(深圳),特聘副研究员

(5)2023.09-至今,中山大学,药学院(深圳),副教授

 

研究方向

(1)胃肠道生理及口服药物递送系统

(2)局部长滞留药物制剂

(3)脑-肠轴及神经退行性疾病机制

 

科研项目

(1)2021.01-2023.12,经费来源:国家自然科学基金青年项目,24万,主持。

(2)2020.10-2024.10,经费来源:军委科技委重点基础研究项目,2160万(承担:115万),子课题负责人。

(3)2023.04-2024.09,经费来源:横向项目,100万,主持。

(4)2019.01-2021.12,经费来源:高校基本科研业务费青年教师培育项目,7.5万,主持。

 

代表论著

# co-first author; * co-correspondence author.

[1].Shu Liang#, Lingyun Xiao#, Yixuan Fang, Tian Chen, Zhangwen Peng, Meiying Wu, Yang Liu, Julin Xie, Xizhe Zhao, Yichu Nie, Wenbin Deng, Chao Zhao*, Yang Deng*, Yang Mai*. A nanocomposite hydrogel for co-delivery of multiple anti-biofilm therapeutics to enhance the treatment of bacterial biofilm-related infections. Int. J. Pharm., 2023, 123638.

[2].Francesca K.H. Gavins#, Liu Dou#, Yujia Qin#, Christine M. Madla, Sudaxshina Murdan, Abdul W. Basit, Yang Mai*, Mine Orlu*. Prandial state and biological sex modulate clinically relevant efflux transporters to different extents in Wistar and Sprague Dawley rats. Biomed Pharmacother, 2023, 160: 114329.

[3].Yang Mai#*, Christine M Madla#, Haibin Shao#, Yujia Qin, Hamid Merchant, Sudaxshina Murdan, Abdul W. Basit*. Sex-specific effects of excipients on oral drug bioavailability. Int. J. Pharm., 2022, 629: 122365.

[4].Yang Mai#, Yaqi Ouyang#, Mian Yu, Yujia Qin, Michael Girardi, W. Mark Saltzman, Emiliano Cocco, Chao Zhao, Liu Yu, Yizhen Jia, Lingyun Xiao, Liu Dou, Wenbin Deng, Yang Liu*, Julin Xie*, Yang Deng*. Topical formulation based on disease-specific nanoparticles for single-dose cure of psoriasis. J. Control. Release, 2022, 12; 349:354-366.

[5].Yang Mai#, Yaqi Ouyang#, Yujia Qin, Changchang Jia, Laura E. McCoubrey, Abdul W. Basit, Yichu Nie, Yizhen Jia, Liu Yu, Liu Dou, Wenbin Deng, Yang Deng*, Yang Liu*. Poly(lactic acid)-hyperbranched polyglycerol nanoparticles enhance bioadhesive treatment of esophageal disease and reduce systemic drug exposure. Nanoscale, 2022, 14(23):8418-8428.

[6].Christine M. Madla#, Yujia Qin#, Francesca K. H. Gavins, Jing Liu, Liu Dou, Mine Orlu, Sudaxshina Murdan, Yang Mai*, Abdul W. Basit*. Sex differences in intestinal P-glycoprotein expression in Wistar versus Sprague Dawley rats. Pharmaceutics, 2022, 14, 1030.

[7].Changchang Jia#, Fan Zhang#, Jiamei Lin#, Liwen Feng, Tiantian Wang, Yuan Feng, Feng Yuan, Yang Mai*, Xiaowei Zeng*, Qi Zhang*. Black phosphorus-Au-thiosugar nanosheets mediated photothermal induced anti-tumor effect enhancement by promoting infiltration of NK cells in hepatocellular carcinoma. J. Nanobiotechnology, 2022, 20: 90.

[8].Yang Mai#, Francesca K.H. Gavins#, Liu Dou, Jing Liu, Farhan Taherali, Manal E. Alkahtani, Sudaxshina Murdan, Abdul W. Basit, Mine Orlu*. A non-nutritive feeding intervention alters the expression of efflux transporters in the gastrointestinal tract. Pharmaceutics, 2021, 13, 1789.

[9].Yang Mai#, Liu Dou#, Zhicheng Yao, Christine M. Madla, Francesca K.H. Gavins, Farhan Taherali, Heyue Yin, Mine Orlu, Sudaxshina Murdan*, Abdul W. Basit*. Quantification of P-glycoprotein in the gastrointestinal tract of humans and rodents: Methodology, Gut Region, Sex and Species Matters. Mol Pharmaceut, 2021, 3;18(5):1895-1904.

[10].Yang Mai, Diane A.I. Ashiru-Oredope, Zhicheng Yao, Liu Dou, Christine M. Madla, Farhan Taherali, Sudaxshina Murdan, Abdul W. Basit*. Boosting drug bioavailability in men but not women through the action of an excipient. Int. J. Pharm., 2020, 587: 119678.